Searches of biological sequences are a central component of both intellectual property management and research analysis. Such searches are critical at many stages of the innovation and commercialization process, particularly in biotechnology and pharmaceuticals. Our team at Citius Minds uses up to date data focused on delivering reliable Patent Sequence Search services while addressing some of the essential goals, such as:
* Patent Prior Art Searches: These searches assist in assessing the novelty (or inventive step) of a given nucleotide or protein sequences to enable the innovators to secure intellectual property protection with assurance.
* Freedom to Operate (FTO) Evaluations: Determining the risk of potential infringement before you commercialize a product or implement a technology requires what is commonly known as FTO searches. We combine qualitative text mining methods with our internal dataset to identify patents and published applications that potentially could raise the legal system towards blocking access and/or use of the sequence of interest, to provide a greater understanding of the pertinent intellectual property landscape.
* Competitive Intelligence & Recent Developments: Our services include a summary of recent developments related to a biological sequence of interest. This intelligence helps organizations make more informed decisions by putting the most relevant and timely context around which knowledge to pursue, such as new research, an application for a patent, or to enter the market.
Citius Minds also provides world-class search for biological sequences, utilizing advanced databases, proprietary algorithms and domain expertise. With you focussing on the more essential task, our services help you with patent protection, FTO analysis, and new technology monitoring impacting your business domain.
Two types of sequence-related patent searches focus on nucleic acid sequences (DNA + RNA) and amino acid sequences ( proteins + peptides). It is thus imperative to discuss a thorough review of all the (patent and non-patent) literature, which is continuing to grow at an alarming rate. The sequence alignment and database navigation abilities of professionals like bioinformaticians are deep into our expertise.
At Citius Minds, we have the right solution to the problem of biological sequences searches. We also work on both nucleotide and protein sequences and utilize the latest tools and databases for complete information.
We conduct comprehensive searches with a diverse array of specialized tools and databases, such as:
* NCBI-BLAST: Nucleotide & protein sequences comparison to the large data bases.
* UNIPROT: a comprehensive protein sequence and functional information database
* Expasy: A bioinformatics resource portal for life sciences.
* EMBL: For nucleotide sequence data retrieval.
* RSCB-PDB: the RCSB Protein Data Bank, a source of 3D structural data for proteins and nucleic acids.
* Patent Lens: Open database for sequence and patent analysis, free.
* Commercial Databases: The online resources like PCTgene, Dgene, STN or GenomeQuest that allow more powerful searches for sequences.
We thoroughly analyze all the biological steps in the process through a systematic approach. Citius Minds has generated accurate and informative outputs either in terms of estimating patentability, reducing the risk of commercialization or gaining knowledge on various innovative sequences.
Chief Scientist, Biotechnology Company
A global biotechnology company was planning to patent a novel genetic sequence they had developed for a crop resistant to extreme weather conditions. The sequence encoded a specific protein that enhanced the plant’s ability to withstand drought and heat stress. The client wanted to ensure that their sequence was novel and did not infringe upon any existing patented sequences.
Our team began by thoroughly understanding the biological functions and structure of the disclosed genetic sequence. Using advanced bioinformatics tools and proprietary sequence search databases, we identified homologous and similar sequences in existing patents and scientific literature. Our search strategy involved using BLAST-based algorithms, keyword combinations, and specific genetic markers to detect prior art.
We discovered a closely related sequence patented for a different use—enhancing photosynthesis in algae. Although it shared significant structural similarities with the client’s sequence, our detailed comparison identified notable differences in the functional domains and claims of the existing patents. We provided a report that included:
* A sequence alignment matrix highlighting similarities and differences.
* A comparative analysis of claims and their scope.
* Suggestions for drafting claims that would differentiate the client’s sequence
The client used our findings to amend their claims, focusing on the drought-resistant function of their sequence. This enabled them to secure a robust patent while avoiding potential infringement. Additionally, they leveraged our report to identify licensing opportunities for non-overlapping uses of the sequence.
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A patent sequence search focuses on identifying patents and patent applications that involve biological sequences, such as DNA, RNA, or protein sequences. This type of search involves querying sequence databases to find similarities or exact matches to sequences within patented claims.
Sequence searches are crucial for biotech and pharmaceutical companies to ensure that their research on biological sequences does not infringe upon existing patents. These searches help determine whether certain sequences are already protected, and provide insight into potential areas for innovation.
We utilize specialized databases that house patented biological sequences, such as NCBI, PatSeq, and others. The sequence is searched for exact or partial matches, and the results are analyzed to identify relevant patents or applications that could pose infringement risks or opportunities for licensing.
Both nucleotide sequences (DNA and RNA) and protein sequences can be searched. These include naturally occurring sequences as well as synthetic, modified, or engineered sequences that are commonly found in biotech inventions.
Typically, it takes 1 to 2 weeks, depending on the complexity of the sequence and the scope of the search. For particularly large or complex sequences, it may take a bit longer to complete the search and thoroughly analyze the results.
Yes, a patent sequence search can identify sequences covered by existing patents, which could indicate potential infringement risks. This helps researchers or companies avoid using patented sequences without proper licensing or design-around efforts.
Conducting a sequence search before filing a patent application helps identify prior art and enables drafting more precise claims. It ensures that the claims are not too broad and overlap with existing patented sequences, increasing the chances of the application being approved.
We use databases like PatSeq, GenBank, and various national patent offices that store biological sequence information. These databases are critical in ensuring comprehensive coverage of biological sequence prior art.
The cost varies based on the complexity of the sequence and the depth of analysis required. At Citius Minds, we provide custom quotes based on the scope of each project, ensuring you get the best value for your specific needs.
Yes, by identifying patents that cover specific sequences, companies can explore potential licensing opportunities or collaborations with the patent holders. This is especially useful in industries where sharing technologies or co-developing products is common.